What is the life expectancy of someone with Kartagener syndrome?

In severe cases, the prognosis can be fatal if bilateral lung transplantation is delayed. Fortunately, primary ciliary dyskinesia and Kartagener syndrome usually become less problematic near the end of the patient’s second decade, and many patients have near normal adult lives.

What is Kartagener’s Syndrome?

Kartagener’s syndrome is a subset of primary ciliary dyskinesia, an autosomal recessive inherited disorder characterized by the clinical triad of chronic sinusitis, bronchiectasis, and situs inversus.

Can adults get PCD?

Primary ciliary dyskinesia (PCD) is widely recognized as an aetiology of bronchiectasis not only in children or young adults but also in older patients [9,10,11].

Is Kartagener syndrome rare?

Kartagener’s syndrome is a rare, autosomal recessive genetic ciliary disorder comprising the triad of situs inversus, chronic sinusitis, and bronchiectasis.

What is Young’s syndrome?

Young’s syndrome, also known as azoospermia sinopulmonary infections, sinusitis-infertility syndrome and Barry-Perkins-Young syndrome, is a rare condition that encompasses a combination of syndromes such as bronchiectasis, rhinosinusitis and reduced male fertility.

How many people in the world have primary ciliary dyskinesia?

Primary ciliary dyskinesia occurs in approximately 1 in 16,000 individuals.

What is PCD in pregnancy?

PCD is characterized by chronic upper and lower respiratory tract disease, infertility/ectopic pregnancy, and situs anomalies, that occur in ≈50% of PCD patients (Kartagener syndrome), and these may be associated with congenital heart abnormalities.

Is COPD a PCD?

PCD may first be diagnosed as asthma, chronic bronchitis, smoking-related chronic obstructive pulmonary disease (COPD), or bronchiectasis of unknown cause.

Is there a cure for Kartagener syndrome?

There is no cure for Kartagener syndrome. Treatment varies based on the signs and symptoms present in each person but may include airway clearance therapy and antibiotics .