What is TEG with platelet Mapping?
Thromboelastography with platelet mapping (TEG-PM) is a modality to measure platelet function, especially in patients taking antiplatelet medications. It consists of two components: arachidonic acid (AA), which is sensitive to aspirin, and adenosine diphosphate (ADP), which is sensitive to clopidogrel.
What is platelet Mapping used for?
The whole blood TEG® Platelet Mapping™ assay measures clot strength as maximal amplitude (MA) and enables for quantification of platelet function, including the contribution of the adenosine diphosphate (ADP) and thromboxane A2 (TxA2) receptors to clot formation.
What does a TEG show?
TEG is a non-invasive test that quantitatively measures the ability of whole blood to form a clot. The principle of this in vitro test is to detect and quantify dynamic changes of the viscoelastic properties of a blood sample during clotting under low shear stress.
What is a TEG form?
TEG is a real time analyser of whole blood that can quickly provide patient results to allow for faster treatments and decision-making. TEG can express function and pinpoint dysfunction in the haemostatic process. By doing so, it can reference the types and amounts of blood products to stop bleeding.
How do you read a TEG test?
If we interpret our TEG values:
- R time 20.0 => well above the upper limit of normal (10.0 minutes) = significantly prolonged time for clot formation.
- K time 13.2 => normal: up to 10.0 = prolonged fibrin cross-linking.
- a-angle 16.5 => normal >53.0 = limited clot formation.
How do you interpret TEG results?
How is TEG performed?
In this assay, a standard TEG is run using patient’s whole blood. Then, separate assays are run using the patient’s blood with added AA or ADP. The contribution of fibrin to the MA is subtracted using a mathematical formula. This allows determination of the MA (AA) and MA (ADP), respectively.
How does a TEG test work?
How do you read TEG results?
How is a TEG done?
How is TEG with platelet mapping performed?
TEG with Platelet Mapping •Platelet function is analyzed using the TEG/PM assay. –Four individual samples of 360 µL of whole blood are placed into separate specialized cups from blue-capped collection tubes.
What is the Teg/pm assay for platelet function?
•Platelet function is analyzed using the TEG/PM assay. –Four individual samples of 360 µL of whole blood are placed into separate specialized cups from blue-capped collection tubes. Next, 10 µL of the prepared activator solution, comprised of reptilase, factor XIIIa, and phospholipids are added to three of the cups –CUP 1: Kaolin (TEG Tracing –MA
What is thromboelastography with platelet mapping?
Thromboelastography (TEG) with platelet mapping (PM) is an alternative assay that directly measures clot formation and mechanical strength.
What is the percent platelet receptor inhibition for TEG platelet mapping?
Table 1 TEG® Platelet Mapping™ assay variables (see text) and percent platelet receptor inhibition for healthy blood donors. The CV a values were 3.5% for MA Thrombin , for MA Fibrin it was 5.2%, for MA ADP 6.6 %, and for MA AA 4.5%.
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