What is endometrial metaplasia?

Endometrial epithelial metaplasia refers to the replacement of the normal endometrial glandular epithelium by cells that are either not encountered in the normal endometrium or, if present, are usually inconspicuous elements.

What is eosinophilic metaplasia?

Eosinophilic metaplasia is an uncommon form of differentiation characterized by an oxyphilic appearance to the individual cells. Eosinophilic metaplasia bears some resemblance to tubal metaplasia, but is devoid of cilia.

What does tubal metaplasia mean?

Comments: It refers to the presence of large number of tubal-type ciliated cells in the endometrial mucosa. It is usually an incidental finding but is seen more commonly in association with endometrial hyperplasia. It may result in abnormal cells in a Pap smear.

What causes tubal metaplasia?

Tubal metaplasia occurs in setting of estrogen excess or postmenopausal. Squamous metaplasia frequently occurs in hyperplasia, neoplasia, CEMI. The endometrium looks very much like the epithelium of the fallopian tube. Cilia are present.

Is endometrial hyperplasia cancerous?

Endometrial hyperplasia is an increased growth of the endometrium. Mild or simple hyperplasia, the most common type, has a very small risk of becoming cancer. It may go away on its own or after treatment with hormone therapy. If the hyperplasia is called “atypical,” it has a higher chance of becoming a cancer.

Is Tubal metaplasia precancerous?

It is generally known that endometrial tubal metaplasia is a benign disease. However studies propose endometrial tubal metaplasia to be a potential premalignant endometrial lesion and its association with endometrial hyperplasia and well-differentiated endometrioid carcinoma.

Is Tubal metaplasia normal?

Although atypical tubal metaplasia is presumed to be reactive or degenerative in etiology, its clinical significance is unknown.

How serious is endometrial hyperplasia?

When the endometrium, the lining of the uterus, becomes too thick, it is called endometrial hyperplasia. This condition is not cancer, but in some cases, it can lead to cancer of the uterus.