What is Beta-Hydroxybutyrate blood test?

Beta-Hydroxybutyrate is the most predominate ketone present during DKA and trends with a patient’s clinical status. Since the Beta-Hydroxybutyrate assay is quantitative it can be used for monitoring ketosis to resolution, making it the superior ketone test.

What does high B hydroxybutyrate mean?

Elevated levels beta-hydroxybutyrate is diagnostic of ketoacidosis, whereas the absence of concomitant hyperglycemia supports the diagnosis of alcoholic ketoacidosis (AKA). Levels ³ 3 mmol/L are indicative of ketoacidosis.

What is normal range for Beta-Hydroxybutyrate?

0.4-0.5 mmol/L
The reference range is less than 0.4-0.5 mmol/L. Levels of more than 1 mmol/L require further action, whereas levels of more than 3 mmol/L require immediate medical review.

Does Beta-Hydroxybutyrate mean DKA?

Beta-hydroxybutyrate is the main metabolic product in ketoacidosis. Levels correlate better with changes in arterial pH and blood bicarbonate levels than ketones, and were found to lead to better outcomes in one study of children.

How do you read a beta-hydroxybutyrate test?

Interpretation

1. The beta-hydroxybutyrate (BHB)/acetoacetate ratio is typically between 3:1 and 7:1 in severe ketotic states.
2. Serum BHB increases in response to fasting, but should not exceed 0.4 mmol/L following an overnight fast (up to 12 hours).

What labs indicate DKA?

Laboratory findings consistent with the diagnosis of diabetic ketoacidosis (DKA) include blood pH < 7.3, serum bicarbonate < 18 mEq/L, anion gap > 10 mEq/L and increased serum osmolarity.

Why is my beta-hydroxybutyrate high?

What does it mean if your Beta-Hydroxybutyrate result is too high? Elevated β-Hydroxybutyrate is a sign that extra chromium and vanadium may be warranted. It is also a byproduct of ketosis. Ketosis occurs when cells do not get a steady supply of sugar from dietary carbohydrate, so they burn fat instead.

How do you interpret beta-hydroxybutyrate?

How do you read C peptide results?

A low level (or no C-peptide) indicates that your pancreas is producing little or no insulin.

1. A low level may be normal if you have not eaten recently. Your blood sugar and insulin levels would naturally be low then.
2. A low level is abnormal if your blood sugar is high and your body should be making insulin at that time.

Does beta-hydroxybutyrate put you in ketosis?

Most people naturally experience a mild state of ketosis during periods of fasting or strenuous exercise ( 2 , 3 ). The two main ketone bodies produced during ketosis are acetoacetate and beta-hydroxybutyrate.

What does BH mean in a blood test?

BH. Iron binding capacity, serum. BIOCHEMISTRY, HAEMOPOITEIC TESTS.

Is potassium low or high in DKA?

Patients in DKA are low in total body potassium and their serum concentration is falsely elevated due to extracellular shift. On average, patients will have a potassium deficit of 3-5 mEq/kg.

What causes elevated beta hydroxybutyrate?

Elevated serum β-hydroxybutyrate levels can be observed in various conditions associated with metabolic substrate use disorders, insulin deficiency, and altered redox status including the following: Diabetic ketoacidosis: Ketone body production is stimulated by dehydration and insulin deficiency.

What is normal beta hydroxybutyrate?

The normal beta hydroxybutyrate levels in serum are less than 3 mg/dl while the normal beta hydroxybutyrate levels in blood are between 0.21 to 2.8 mg/dl.

What is a beta hydroxybutyrate test?

The beta-hydroxybutyrate blood test helps check for ketosis and is used by people performing ketogenic diets.

What does a high level of beta-hydroxybutyrate mean?

Elevated levels beta-hydroxybutyrate is diagnostic of ketoacidosis, whereas the absence of concomitant hyperglycemia supports the diagnosis of alcoholic ketoacidosis (AKA). Levels ³ 3 mmol/L are indicative of ketoacidosis. In very severe diabetic ketoacidosis (DKA), the beta-hydroxybutyrate serum concentration may exceed 25 mmol/L.