What does Tachyphylactic mean?

What does Tachyphylactic mean?

From Wikipedia, the free encyclopedia. Tachyphylaxis (Greek ταχύς, tachys, “rapid”, and φύλαξις, phylaxis, “protection”) is a medical term describing an acute, sudden decrease in response to a drug after its administration; i.e. a rapid and short-term onset of drug tolerance.

What causes Tachyphylaxis?

Tachyphylaxis tends to develop quickly over a short period. It occurs when a person’s response to repeated doses of a medication rapidly decreases over a short period. The condition is also known as acute drug desensitization and can occur with any drug.

What does the medical term Angio mean?

Angio- is a combining form used like a prefix meaning “vessel” or “container.” It is used in medical and scientific terms. In anatomy, angio- specifically refers to blood and lymphatic vessels.

What drugs cause Tachyphylaxis?

Over-the-counter ophthalmic decongestant drops, such as Visine (Pfizer), are another category of drugs that induce tachyphylaxis. In particular, these medications contain alpha-adrenergic amines—such as tetrahydrozoline, naphazoline or phenylephrine—that act as vasoconstrictors.

What does term bioavailability mean?

The ability of a drug or other substance to be absorbed and used by the body. Orally bioavailable means that a drug or other substance that is taken by mouth can be absorbed and used by the body.

How is tachyphylaxis treated?


  1. Increasing the current antidepressant dose.
  2. Drug holidays or decreasing the current antidepressant dose.
  3. Changing antidepressant drugs (to the same mechanism or a different mechanism of action).
  4. Augmentation strategies for ADT tachyphylaxis.

Are drugs teratogens?

Certain drugs such as alcohol, some illegal drugs, and some prescription and over-the-counter medications are known to cause birth defects if taken during pregnancy. Drugs that can cause birth defects are called ‘teratogens’.

Why Angio is done?

Angiography is used to check the health of your blood vessels and how blood flows through them. It can help to diagnose or investigate several problems affecting blood vessels, including: atherosclerosis – narrowing of the arteries, which could mean you’re at risk of having a stroke or heart attack.

How do you prevent tachyphylaxis?

Cardiovascular System Tolerance, termed tachyphylaxis, develops quickly to the effects of nitrates. To prevent tolerance from occurring there should be a nitrate-free interval (at least 12 hours) during each 24-hour period (typically overnight).

What is pharmacodynamics and pharmacokinetics?

In simple words, pharmacokinetics is ‘what the body does to the drug’. Pharmacodynamics describes the intensity of a drug effect in relation to its concentration in a body fluid, usually at the site of drug action. It can be simplified to ‘what the drug does to the body’.

What is the meaning of tachyphylaxis?

Medical Definition of tachyphylaxis. : diminished response to later increments in a sequence of applications of a physiologically active substance (as the diminished pressor response that follows repeated injections of renin)

Can tachyphylaxis occur after a small dose of medication?

It can occur after an initial dose or after a series of small doses. Increasing the dose of the drug may be able to restore the original response. Tachyphylaxis is characterized by the rate sensitivity: the response of the system depends on the rate with which a stimulus is presented.

What is rate sensitivity in tachyphylaxis?

Tachyphylaxis is characterized by the rate sensitivity: the response of the system depends on the rate with which a stimulus is presented. To be specific, a high-intensity prolonged stimulus or often-repeated stimulus may bring about a diminished response also known as desensitization.

What is tachyphylaxis in menopause?

Tachyphylaxis has been reported in some women taking subcutaneous hormone-replacement therapy, in whom menopausal symptoms recur in the face of normal serum oestrogen levels. Segen’s Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.