What are pooled platelets?

What are pooled platelets?

Pooled platelets, a blood component product, are derived from the whole blood donations of 4–6 donors. When derived from whole blood, each individual platelet concentrate contains roughly 5.5 × 1010 platelets, which necessitates pooling to achieve a therapeutic platelet dosing for adult patients.

What is difference between SDP and RDP?

What is the Difference Between SDP and RDP? SDP is a platelet transfusion method in which platelets are prepared from a single donor by an apheresis machine. RDP is a platelet transfusion method in which platelets are prepared by centrifuging the whole blood collected from four to five donors and pooling the platelets.

What is apheresis plasma?

Apheresis is used for the collection of donor blood components (such a platelets or plasma) as well as for the treatment for certain medical conditions in which a part of the blood that contains disease-provoking elements is removed. Apheresis is also called pheresis or hemapheresis.

What does platelet apheresis mean?

Listen to pronunciation. (a-feh-REE-sis) A procedure in which blood is collected, part of the blood such as platelets or white blood cells is taken out, and the rest of the blood is returned to the donor. Also called pheresis.

How are platelets pooled?

Whole blood pooled platelets are obtained by pooling buffy coats from four separate ABO- identical whole blood donations using a platelet additive solution (PAS). The pool is centrifuged, filtered (to remove white cells) and rested (to prevent platelet clumps) to produce a leucodepleted pooled platelet unit.

What is the benefit of apheresis?

The main advantage of apheresis collections are that more than one dose of platelets or red cells can be collected from one donor per donation, thus reducing patient exposure to multiple donors.

Which is more effective SDP or RDP?

Efficacy: One unit of platelet RDP increases platelet count by approximately 5 x 109/L (i.e. 5000/mm3). SDP is as effective as RDP. SDP is more expensive & its use should be limited to cases of platelet refractoriness & in limiting donor exposure.

How many platelets are in one unit of SDP?

The Platelets so collected are called Single Donor Platelets (SDP). Single Donor Platelets are more potent than Random Donor Platelets. 1 unit of Single Donor Platelets is equivalent to 6-8 units of Random Donor Platelets.

What is the difference between pheresis and apheresis?

Pheresis is from the Greek and means “to take away” while apheresis means “to separate blood.” The terms often are used interchangeably. Pheresis is any procedure in which blood is withdrawn from a donor and a fluid or solid portion (eg, plasma, leukocytes, platelets, cells) is separated and kept.

What are the different types of apheresis?


  • Plasmapheresis – blood plasma.
  • Erythrocytapheresis – red blood cells.
  • Plateletpheresis (thrombapheresis, thrombocytapheresis) – blood platelets.
  • Leukapheresis – leukocytes (white blood cells).
  • Stem cell harvesting – circulating bone marrow cells are harvested to use in bone marrow transplantation.

Is apheresis the same as plasma donation?

Platelet, double red cell and plasma donations are each a type of apheresis — a method of collecting blood in which you’re hooked up to a machine that collects and separates blood components (red cells, platelets and plasma) and returns unused components to you.

Why is platelet apheresis?

Apheresis is the process of separating blood into its different components: Platelets, Red Blood Cells (RBCs) and Plasma. Platelet donations allow us to collect what our patients need and return the rest of the blood to the donor. PLATELETS are essential for blood clotting.

What diseases can be treated with apheresis?

Goodpasture’s Syndrome. Goodpasture’s syndrome is a type of autoimmune disease that typically affects individuals over sixty or those in early adulthood.

  • Waldenstrom’s Macroglobulinemia.
  • Leukemia.
  • Hyperviscosity Syndrome.
  • Rheumatoid Arthritis.
  • What is therapeutic apheresis used for?

    Therapeutic apheresis (TA) is helpful for patients facing a variety of medical conditions. It can be used to treat patients with blood disorders, kidney problems, metabolic diseases, and neurologic disorders. It is also indicated in patients with autoimmune diseases.

    What is the unit of platelets?

    Whole blood derived platelets should contain a minimum of 5.5 x 1010 platelets per unit with an overall volume of around 50 mL. Apheresis platelets should contain a minimum of 3 x 1011 platelets per unit with an overall volume around 300 mL. Transfused platelets have an expected life-span of 3-4 days.

    What is the unit of platelet count?

    It is the quantity of platelets that circulate in the blood stream for every microliter of blood. Laboratory values and platelet count units of measurement is per cubic millimeter (a mm3equals a microliter).