What are flocculated suspensions?

What are flocculated suspensions?

A flocculated suspension is a suspension in which particles of the suspension has undergone flocculation. Flocculation is the process in which colloids in a suspension can be obtained in an aggregated form. Sedimentation is the settling down of aggregates or particles of suspension to the bottom of the liquid.

Which suspension forms hard cake on storage?


Flocculated suspension Deflocculated suspension
Sediment is loosely packed and does not form a hard cake. Sediment is tightly packed and forms a hard cake.
The supernatant is clear. The supernatant is hazy.
Floccules stick to the sides of the bottle. Particles do not stick to the sides of the bottle.

What is flocculated suspension in pharmacy?

Flocculated suspension No caking formation – since flocs – Loose aggregates so re-disperse easily on normal shaking. More stable pharmaceutical suspension.

What is the difference between flocculated and non flocculated suspension?

The suspension are said to be flocculated ,when the individual particles are in contact with each other and form a network like structure . Whereas in case of non-flocculated suspensions,the individual particles exists as a separate entity. In Non-flocculated suspensions- Particles exist as separate entities.

What are diffusible suspensions?

Suspension containing diffusible substances • They contain easily dispersible solids • They are light and easily wettable substances • Readily mixed with water and on shaking diffuse evenly throughout the liquid long enough to ensure even distribution and a dose to be measured 9.

Which is incorrect for flocculated suspension?

A. Particles form loose aggregate structure .

Why suspended particles become Flocculated in a suspension?

Answer: Ionic surfactants cause flocculation by neutralizing the charge on each particle, resulting into a flocculated suspension. When the surfactants reduce the interfacial tension, the liquid becomes capable of displacing the adsorbed film of air from the surface of solid drug particle and facilitating wetting.

What is Indiffusible suspension?

Suspensions containing indiffusible solids • These are insoluble powders and will not remain evenly distributed in a vehicle long enough to ensure uniformity of dose • These sediment too rapidly and require the addition of other materials to reduce sedimentation rate to an acceptable level.

What are flocculated and deflocculated suspensions?

Suspensions can be divided into two groups as flocculated suspensions and deflocculated suspensions based on electro-kinetic nature of solid particles that are suspended in the suspension. In chemistry, flocculation is the process in which colloids in a suspension can be obtained in an aggregated form.

How to prepare suspension without flocculating agent?

Electrolyte and ionic surfactant can be used as flocculating agents to produce a flocculated suspension.suspension prepared without flocculating agent is a deflocculated one. The physical stability of the suspension is assist by determining the sedimentation volume or degree of flocculation.

What is an example of a concentrated suspension?

For example cortisone acetate, prednisolone acetate  Concentrated suspension (50%w/v solid). For example zinc oxide suspension 3-Based on behavior of Dispersed Phase:  Flocculated Suspension (Dispersed phase maybe a network of particle)  Deflocculated Suspension (Dispersed phase may consist of discrete particles)

What are the different types of suspension?

This dosage form is used for providing a liquid dosage form for insoluble drugs (hydrophobic drugs). Suspensions can be classified into flocculated and deflocculated suspensions based on the electrokinetic nature of the dispersed phase. In this article the following key areas will be covered; 1. Flocculated suspension 2. Deflocculated suspension 3.