Does propafenone affect the liver?

Does propafenone affect the liver?

Propafenone has not been linked to acute liver failure, chronic liver injury or vanishing bile duct syndrome. Recurrence upon reexposure is common and should be avoided. There is no evidence for cross sensitivity to the hepatic injury of propafenone with other antiarrhythmic agents.

What are the side effects of the drug propafenone?

Side Effects

  • Chest pain.
  • fast, irregular, or slow heartbeat.
  • lightheadedness, dizziness, or fainting.
  • shortness of breath.
  • swelling of the feet or lower legs.
  • weight gain.

How long does it take to get propafenone out of your system?

Propafenone’s average elimination half-life was 6 hours (range 2.4 to 11.8).

What can you not take with propafenone?

Grapefruits and grapefruit juice may increase the effects of propafenone by increasing the amount of this medicine in your body. You should not eat grapefruit or drink grapefruit juice while you taking this medicine. Tell your doctor if you are smoking tobacco.

How do I cancel my propafenone?

If you have been using this medicine regularly for several weeks, do not suddenly stop using it. Check with your doctor for the best way to gradually reduce the amount you are taking before stopping completely. This medicine may decrease the amount of sperm men make. Talk to your doctor if you have concerns about this.

Is there an alternative to propafenone?

The shortage of propafenone may have led to the shortfall of flecainide. For instance, medSask, a Saskatchewan drug information program, was recommending flecainide as an alternative to propafenone when that drug ran out, says Carmen Bell, a pharmacist with the service.

Can you exercise on propafenone?

At exercise, propafenone significantly decreased heart rate (−6%, P < 0.05), systolic blood pressure (−6%, P < 0.05), and the rate–pressure product (−11%, P < 0.05). Plasma concentrations of propafenone increased during exercise (+23%, P < 0.05) and decreased during recovery (−33%, P < 0.05).

What side effects are associated with the use of Prevacid?

Summary. Side effects associated with Prevacid are generally mild when this medication is taken appropriately according to the manufacturer’s guidelines.

  • Common Prevacid Side Effects. Most side effects of Prevacid are moderate and manageable.
  • Serious Prevacid Side Effects.
  • Prevacid and Broken Bones.
  • Does Rythmol lower heart rate?

    Heart rate decreased is found among people who take Rythmol, especially for people who are female, 60+ old, have been taking the drug for < 1 month. The phase IV clinical study analyzes which people take Rythmol and have Heart rate decreased.

    What are the side effects of ‘respidone ‘?

    In Summary. Commonly reported side effects of risperidone include: agitation, akathisia, anxiety, constipation, dizziness, drowsiness, dystonia, extrapyramidal reaction, nausea, rhinitis, and weight gain. Other side effects include: abdominal pain, sialorrhea, skin rash, tachycardia, and xeroderma.

    Can propafenone cause irregular heartbeat?

    Propafenone may also cause life-threatening irregular heartbeat and increase the risk of death in certain patients. Tell your doctor if you have had a heart attack within the past two years or if you have heart disease. Because of the risks of taking propafenone, it should be used only to treat life-threatening irregular heartbeat.