Which of the following are side effects of dornase alfa administration?
Common side effects may include:
- sore throat;
- chest pain, trouble breathing;
- changes in the sound of your voice;
- rash;
- eye redness; or.
- fever.
Does dornase alfa have many adverse effects?
If you experience any of the following serious side effects while taking dornase alfa, seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); increased difficulty breathing; chest pain; or.
What drug class is dornase alfa?
Enzyme
Dornase alfa/Classification
What are the nursing implications for guaifenesin?
Guaifenesin is only recommended for use during pregnancy and breastfeeding when benefit outweighs the risk. Guaifenesin may cause a skin rash, headache, nausea, and vomiting. Patients should take care to avoid irritants that stimulate their cough. Additionally, the medication can cause drowsiness.
What is dornase alfa solution used for?
Dornase alfa inhalation solution is used together with other medicines (eg, antibiotics, bronchodilators, and steroids) to control symptoms of cystic fibrosis. Cystic fibrosis is a condition in which a thick mucus is formed in the lungs and breathing passages.
Is dornase alfa expensive?
There is currently no generic for Pulmozyme (dornase alfa), so it can be expensive, even with insurance. GoodRx coupons, copay cards and patient assistance programs may help lower the cost.
What is dornase alfa used for?
When do you use dornase alfa?
Dornase alfa is a synthetic protein that breaks down excess DNA in the pulmonary secretions of people with cystic fibrosis. Dornase alfa is used to improve lung function in people with cystic fibrosis by thinning pulmonary secretions and reducing the risk of respiratory tract infections.
Can you take guaifenesin while nursing?
The expectorant guaifenesin and the cough suppressant dextromethorphan are often found together in products like Mucinex DM or Robitussin DM. Both of these medications are okay to take while breastfeeding.
What are the contraindications of guaifenesin?
Who should not take GUAIFENESIN DAC?
- overactive thyroid gland.
- diabetes.
- closed angle glaucoma.
- high blood pressure.
- significant uncontrolled high blood pressure.
- severe disease of the arteries of the heart.
- enlarged prostate.
- an inability to completely empty the bladder.
What is the purpose of dornase alfa which is often prescribed for a patient with CF?
Dornase alfa is used to reduce the number of lung infections and to improve lung function in patients with cystic fibrosis. It breaks down the thick secretions in the airways, allowing air to flow better and preventing bacteria from building up.
How effective is dornase alfa?
Patients treated with dornase alfa had lower pulmonary functions, more bacterial colonization, and more exacerbations at baseline (FEV1 : 76.0% vs 87.6%, Pseudomonas aeruginosa : 64.1% vs 46.7%, pulmonary exacerbations during the previous 6 months: 56.4% vs 22.
Is it safe to take Dornase alfa with other medications?
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take dornase alfa with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What is Dornase alfa used to treat?
It is used to lower the number of lung infections and help lung function in cystic fibrosis. What do I need to tell my doctor BEFORE I take Dornase Alfa? If you have an allergy to dornase alfa or any other part of dornase alfa.
How does Dornase alfa hydrolyze extracellular DNA?
MECHANISM OF ACTION Dornase alfa hydrolyzes extracellular DNA. The exact mechanism of hydrolysis is unknown. There is no effect on intracellular DNA.
How is Dornase alfa used to treat atelectasis in premature babies?
Small case series have described the use of dornase alfa for the treatment of severe atelectasis and mucus plugging in premature neonates as young as 25 weeks postmenstrual age. Nebulized doses have ranged from 1.25 mg as a single dose to 2.5 mg twice daily.
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