What is slc25a51?

SLC25A51 is a mammalian mitochondrial NAD + transporter. SLC25A51 is a mammalian mitochondrial NAD. +. transporter. Nature. 2020 Sep 9. doi: 10.1038/s41586-020-2741-7. Online ahead of print.

What does SLC25 stand for?

The mitochondrial transporter family (SLC25): physiological and pathological implications. In: Hediger, M.A. (Ed.), “The ABC of solute carriers”, Pflugers Arch. Eur. J. Physiol. 447, 689–709.

What do all SLC25 members have in common?

Though MCs display a great diversity of transported solutes (i.e., a large variety of metabolites, nucleotides and coenzymes), all SLC25 members have common sequence features: a tripartite structure, a 3-fold repeated signature motif, and six transmembrane α-helices (two in each of the three repeats).

What are the K M and K I of SLC25A17?

The K m of SLC25A17 for AMP is 0.19 mM and the inhibition constants (K i) for CoA, FAD, FMN, NAD +, PAP and ADP are 19.6 μM, 2.6 μM, 10.2 μM, 0.85 mM, 0.78 mM and 0.6 mM, respectively.