What is Edecrin used for?

This medication is used to decrease swelling (edema) caused by conditions such as cancer, congestive heart failure, liver disease, and kidney disease. This effect can help your kidneys work better and lessen symptoms such as trouble breathing and swelling in your ankles, feet, hands, or belly.

Is there a generic for Edecrin?

Ethacrynic acid (Edecrin) is available as a generic medication and may be significantly cheaper compared to the brand version. Unless there is a specific reason you need the brand, the generic medication will be a better value.

Is Edecrin Ototoxic?

However, in some patients the hearing loss has been permanent. A number of these patients were also receiving drugs known to be ototoxic. EDECRIN may increase the ototoxic potential of other drugs (see PRECAUTIONS, Drug Interactions).

Can acetazolamide cause depression?

Common adverse effects of acetazolamide include the following: paraesthesia, fatigue, drowsiness, depression, decreased libido, bitter or metallic taste, nausea, vomiting, abdominal cramps, diarrhea, black feces, polyuria, kidney stones, metabolic acidosis and electrolyte changes (hypokalemia, hyponatremia).

What drugs should not be taken with spironolactone?

Taking certain pain drugs with spironolactone can result in kidney damage and increased blood pressure….nonsteroidal anti-inflammatory drugs (NSAIDs), such as:

• diclofenac.
• ibuprofen.
• indomethacin.
• ketoprofen.
• ketorolac.
• meloxicam.
• nabumetone.
• naproxen.

What foods should be avoided when taking spironolactone?

Since spironolactone is a potassium-sparing diuretic, you should avoid taking potassium in your supplements or sports drinks and avoid eating too many high potassium foods such as papaya, cantaloupe, prune juice, honeydew melons, bananas, raisins, mangoes, kiwis, oranges, orange juice, tomatoes, tomato juice, white and …

Who makes Edecrin?

*Edecrin is a trademark of Bausch Health Ireland Limited. Do More Good is a trademark of Upsher-Smith Laboratories, LLC.

Should I drink more water when taking spironolactone?

In some cases, people who take spironolactone can become dehydrated. Be sure to drink adequate water while taking spironolactone. Watch for signs of dehydration, including: excessive thirst.

How long does ethacrynic acid stay in your system?

After oral use, diuresis peaks in about 2 hours and lasts about 6 to 8 hours. The sulfhydryl binding propensity of ethacrynic acid differs somewhat from that of the organomercurials. Its mode of action is not by carbonic anhydrase inhibition. Ethacrynic acid does not cross the blood-brain barrier.

What are the ingredients in Edecrin 25 mg?

Edecrin is supplied as 25 mg tablets for oral use. The tablets contain the following inactive ingredients: colloidal silicon dioxide, lactose, magnesium stearate, starch and talc. Intravenous SODIUM Edecrin (ethacrynate sodium) is a sterile freeze-dried powder and is supplied in a vial containing:

How much Edecrin can you take in a day?

The recommended dose is 25 mg (1 tablet) immediately after breakfast. If necessary, this dosage should be carefully increased by amounts of 25 mg (1 tablet) per day until an effective diuresis is achieved. Edecrin should not be given to infants under two years of age.

What is the empirical formula of Edecrin?

Its empirical formula is C 13H 11Cl 2NaO 4 and its structural formula is: EDECRIN is supplied as 25 mg tablets for oral use. The tablets contain the following inactive ingredients: colloidal silicon dioxide, lactose, magnesium stearate, starch and talc.

What are the side effects of Edecrin?

EDECRIN (ethacrynic acid) has little or no effect on glomerular filtration or on renal blood flow, except following pronounced reductions in plasma volume when associated with rapid diuresis. A transient increase in serum urea nitrogen may occur. Usually, this is readily reversible when the drug is discontinued.