What drugs are cytostatic?

What drugs are cytostatic?

Cytostatic and immunosuppressant drugs

  • Alkylating drugs.
  • Antimetabolites.
  • Cytostatic antibiotics.
  • Photodynamic drugs: porfimer, temoporfin.
  • Platinum compounds (SEDA-26, 490): carboplatin, cisplatin, oxaliplatin.
  • Taxanes: docetaxel, paclitaxel (SEDA-21, 463).
  • Topoisomerase inhibitors (SEDA-27, 477)

What are cytostatic drugs used for?

Cytostatics are drugs used to block the growth of cancer cells. They achieve this by influencing cell metabolism during the cell cycle (Fig. 1) so that cell division and cell reproduction is inhibited. Cytostatics can be classified according to their action mechanisms and their points of attack.

What are examples of cytotoxic drugs?

Some examples of cytotoxic antibiotics include:

  • anthracyclines such as: doxorubicin (Lipodox) valrubicin (Valstar)
  • non-anthracyclines such as: bleomycin (Blenoxane) dactinomycin (Cosmegen)

What is the meaning of cytotoxic drugs?

Listen to pronunciation. (SY-toh-TOK-sik AY-jent) A substance that kills cells, including cancer cells. These agents may stop cancer cells from dividing and growing and may cause tumors to shrink in size.

Is cytostatic chemotherapy?

Cytostatic (or chemotherapeutic) agents (cytostatics) are plant-derived or synthetic substances that can cause death or inhibit growth and dividing of a cell. Cytostatics achieve these growth-inhibiting effects by specific mechanisms of action, which, in one way or another, affect the cells’ metabolism.

Are cytostatic drugs chemotherapy?

Cytotoxic drugs or cytostatics (also cytotoxic chemotherapy) are drugs used to destroy cancer cells. Cytotoxic drugs inhibit cell division and in this way cause cancer cells to die. Cytotoxic drugs are transported in the bloodstream throughout the body.

Is dexamethasone a cytotoxic?

Conclusion: In a bone marrow-derived microenvironment, dexamethasone is five to six times more cytotoxic (on a molar basis) than prednisolone, in agreement with the antiinflammatory activities of these drugs.

Are immunosuppressants cytotoxic?

Cytotoxic drugs prevent cell division or cause cell death. 1 They act predominantly on rapidly dividing cells such as T lymphocytes, and are therefore immunosuppressive and anti-inflammatory.

Is chemotherapy cytotoxic?

What is chemotherapy? Chemotherapy uses anti-cancer (cytotoxic) drugs to destroy cancer cells. Cytotoxic means toxic to cells.

What are the side effects of cytotoxic drugs?

Side effects of cytotoxic drugs

  • Hair loss. The use of certain cytotoxic drugs causes hair growth to stop, which results in either complete or partial baldness and the loss of other bodily hair.
  • Nausea.
  • Damage to the mouth and pharynx mucosa.
  • Diarrhoea.
  • Damage to bone marrow.
  • Chemotherapy sequelae.

Is Methotrexate a cytostatic?

Drug type: Methotrexate is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “antimetabolite.” (For more detail, see “How this drug works” section below).