How do you dilute Bacitracin?

How do you dilute Bacitracin?

Alternatively, reconstitute 50,000 units with 50 mL of 0.9% Sodium Chloride injection to give a solution containing bacitracin 1000 units/mL; further dilute this solution with 50 mL of 2% procaine HCl injection to give a solution containing 500 units/mL.

What is the strength of Bacitracin?

Preparations

Dosage Forms Strengths Brand Names
Ointment Bacitracin Zinc 400 units per g, Neomycin Sulfate 3.5 mg (of neomycin) per g, Polymyxin B Sulfate 5000 units per g, and Lidocaine 40 mg per g* Bacitracin Zinc, Neomycin Sulfate, Polymyxin B Sulfate, and Lidocaine Ointment

How many grams is Bacitracin?

PACKAGE/LABEL PRINCIPAL DISPLAY PANEL – 3.5 g Label

Packaging
# Item Code Package Description
2 NDC:0574-4022-11 1 g in 1 TUBE
3 NDC:0574-4022-35 1 TUBE in 1 CARTON
3 3.5 g in 1 TUBE

What is a unit of Bacitracin?

The International Unit of Bacitracin is defined as the activity of 0.01351 mg of the second International Standard for Bacitracin.

Is bacitracin bacteriostatic or bactericidal?

Bacitracin is a mixture of several closely related cyclic polypeptide antibiotics that has both bacteriostatic and bactericidal properties depending on the concentration of the drug and the susceptibility of the microorganism.

How do you reconstitute polymyxin?

Reconstitution. Reconstitute polymyxin B powder for injection by adding 2 mL of sterile water for injection, 0.9% sodium chloride injection, or 1% procaine hydrochloride injection to vial containing 500,000 units to provide a solution containing approximately 250,000 units/mL.

Is vancomycin bacteriostatic or bactericidal?

While vancomycin is bactericidal against all susceptible Gram-positive pathogens it exerts only bacteriostatic activity against enterococci and needs to be combined with another agent, usually an aminoglycoside, to achieve bactericidal activity.

How is bacitracin made?

Bacitracin is commercially manufactured by growing the bacteria Bacillus subtilis var Tracy I in a container of liquid growth medium. Over time, the bacteria synthesizes the antibiotic and secretes the antibiotic into the medium. The antibiotic is then extracted from the medium using chemical processes.

Does bacitracin work on Gram negative?

Bacitracin is a bactericidal drug that inhibits the formation of linear peptidoglycan chains, which are the main component of bacterial cell membranes. Most Gram-positive bacteria, including staphylococci and C. difficile are sensitive to this drug. At the same time, it has almost no effect on Gram-negative bacteria.

How is bacitracin absorbed?

Topical and ophthalmic forms of bacitracin typically result in minimal absorption through the skin and are considered a low risk to the feeding infant. Only water-soluble creams or gel products should be applied to the breast tissue to prevent infant exposure to mineral paraffin from licking.

How do you mix polymyxin?

Reconstitute 50 mg polymyxin B powder with 10 ml sterile water for injection or NS injection to provide a 0.5% polymyxin B solution. The solution may be further diluted to 50 ml to provide a 0.1% solution. Apply as part of wet dressings or as a topical solution.

How do you dissolve polymyxin?

Dissolve 500,000 polymyxin B units in 2 mL sterile water for injection or sodium chloride injection or procaine hydrochloride injection 1%. Adults and children: 25,000 to 30,000 units/kg/day. This should be reduced in the presence of renal impairment. The dosage may be divided and given at either 4 or 6 hour intervals.

What is bacitracin good for?

Bacitracin is an antibiotic that fights bacteria. Bacitracin topical (for the skin) is used to prevent infection in minor cuts, scrapes, and burns.

Where to buy bacitracin?

Compare prices, print coupons and get savings tips for Bacitracin / Polymyxin B (Generic Ak-Poly-Bac) and other Eye Infection and Bacterial Infection drugs at CVS, Walgreens, and other pharmacies. Prices start at $17.02

What is bacitracin cream?

USES: This medication is used to prevent minor skin infections caused by small cuts, scrapes, or burns. Bacitracin works by stopping the growth of certain bacteria. It belongs to a class of drugs known as antibiotics.This antibiotic only prevents bacterial infections. It will not work for virus or fungus infections.