Does hidradenitis suppurativa affect pregnancy?

Does hidradenitis suppurativa affect pregnancy?

Some researchers found that pregnancy does not change HS symptoms for most women. However, other researchers have found that HS symptoms get worse for some women during pregnancy. Research shows that taking oral zinc may stop HS flares. Zinc reduces inflammation and is safe for unborn babies.

Can hidradenitis cause miscarriage?

Bacterial infection with Staphylococcus, Escherichia coli, and Streptococcus is considered a secondary event in the pathogenesis of HS. These types of bacteria have previously been reported to cause miscarriage in the field of obstetrics and gynecology.

Is clindamycin good for hidradenitis suppurativa?

Topical clindamycin — Topical clindamycin is a well-tolerated therapy that may improve HS through reducing inflammatory lesions. The drug is typically applied two times per day in skin areas subject to recurrent flares. Although frequently prescribed, data to support efficacy of topical clindamycin are limited.

How is hidradenitis suppurativa treated during pregnancy?

Topical (meaning applied to the skin) antibiotics (clindamycin, erythromycin, metronidazole) are the first choice to treat HS for pregnant and nursing mothers. Besides lotion and creams, alcohol-based formulations (gel and solution) are particularly useful as they dry easily after application.

How is HS treated during pregnancy?

What bacteria causes hidradenitis suppurativa?

Bacteria known to cause skin and soft tissue infections were uncovered in microbiological studies of the skin disease hidradenitis suppurativa (HS), with nearly 60% of cultures dominated by Staphylococcus lugdunensis, according to a study published online November 13 in Emerging Infectious Diseases.

Do antibiotics help hidradenitis suppurativa?

Treatment can begin with topical or systemic antibiotics, or both. The only topical antibiotic that has been proven effective in a randomized controlled trial is clindamycin (Cleocin).

How much zinc should I take for hidradenitis suppurativa?

Patients with mild to moderate hidradenitis suppurativa who had all achieved clinical efficacy with a 12-week course of minocycline were given either a maintenance regimen of combination zinc 90 mg and nicotinamide 30 mg daily for 12 weeks or no treatment.

Are contemporary therapies for hidradenitis suppurativa (HS) suitable for pregnant and nursing populations?

Most patients with hidradenitis suppurativa (HS) will continue to be symptomatic during pregnancy; however, current management guidelines are not suitable for pregnant and nursing populations. This review summarizes the suitability of contemporary therapies for HS during pregnancy and lactation.

Can you take clindamycin while pregnant?

Clindamycin Pregnancy Warnings. There are no controlled data in pregnant women during the first trimester of pregnancy. The results of a study have suggested that early second trimester treatment of bacterial vaginosis and abnormal vaginal flora with oral clindamycin may reduce the incidence of preterm delivery and late miscarriage (n=485).

What are the clindamycin breastfeeding warnings?

Clindamycin Breastfeeding Warnings. A report of bloody stools in a 5-day-old breastfed infant may have been caused by the concurrent maternal administration of IV clindamycin and gentamicin. Symptoms resolved 24 hours after breastfeeding was stopped and no further difficulties reported when breastfeeding was resumed on day 6 of age,…

What is the peak concentration of clindamycin in breast milk?

Peak concentrations in breast milk after IV administration of clindamycin 600 mg IV every six hours have been reported at 2.65 mg/L after 3.5 hours and 3.1 mg/L after 30 minutes.