Can meropenem be given intramuscularly?

Can meropenem be given intramuscularly?

Meropenem monotherapy has proved efficacious in the treatment of a variety of infections in adults and children and can be administered by bolus IV injection, as well as IV infusion and intramuscular (IM) injection.

How do you administer imipenem?

Imipenem and cilastatin injection comes as a powder to be mixed with liquid to be injected intravenously (into a vein) or intramuscularly (into a muscle). When imipenem and cilastatin is injected intravenously, it is usually infused (injected slowly) over a period of 20 minutes to 1 hour every 6 or 8 hours.

Which carbapenem can be given IM?

PRIMAXIN I.M. (Imipenem and Cilastatin for Injectable Suspension) is a formulation of imipenem (a thienamycin antibiotic) and cilastatin sodium (the inhibitor of the renal dipeptidase, dehydropeptidase I). PRIMAXIN I.M. is a potent broad spectrum antibacterial agent for intramuscular administration.

Is imipenem given IV?

For Intravenous Injection Only The dosage recommendations for PRIMAXIN represent the quantity of imipenem to be administered. An equivalent amount of cilastatin is also present in the solution. These doses should be used for patients with creatinine clearance of greater than or equal to 90 mL/min.

Can meropenem be given IV push?

Meropenem is usually given by intravenous infusion over approximately 15 to 30 minutes (see section 6.2, 6.3 and 6.6). Alternatively, doses up to 1 g can be given as an intravenous bolus injection over approximately 5 minutes.

How meropenem injection is given?

Meropenem injection comes as a powder to be mixed with liquid and injected intravenously (into a vein). It is usually given every 8 hours. The length of treatment depends on your general health, the type of infection you have, and how well you respond to the medication.

Is imipenem a penicillin?

Imipenem is a beta-lactam antibiotic belongings to the subgroup of carbapenems. Imipenem is active against aerobic and anaerobic Gram positive as well as Gram negative bacteria including Pseudomonas aeruginosa and the Enterococcus. It exerts a bactericidal effects by disrupting cell wall synthesis.

What is imipenem used to treat?

Imipenem and cilastatin combination is used in the treatment of infections caused by bacteria. It works by killing bacteria or preventing their growth. This medicine will not work for colds, flu, or other virus infections.

Is imipenem and carbapenem?

Data synthesis: Imipenem, the first carbapenem, was first marketed in 1987; meropenem was introduced to the market in 1996. In general, imipenem is more active against Gram-positive cocci while meropenem is more active against Gram-negative bacilli. The agents display similar pharmacokinetics.

What is imipenem IMM?

DESCRIPTION. PRIMAXIN I.M. (Imipenem and Cilastatin for Injectable Suspension) is a formulation of imipenem (a thienamycin antibiotic) and cilastatin sodium (the inhibitor of the renal dipeptidase, dehydropeptidase I). PRIMAXIN I.M. is a potent broad spectrum antibacterial agent for intramuscular administration.

What are the pharmacokinetics of imipenem 500 mg and cilastatin 500 mg?

In healthy elderly volunteers (65 to 75 years of age with normal renal function for their age), the pharmacokinetics of a single dose of imipenem 500 mg and cilastatin 500 mg administered intravenously over 20 minutes are consistent with those expected in subjects with slight renal impairment for which no dosage alteration is considered necessary.

What are the systemic side effects of imipenem?

Systemic Adverse Reactions. The most frequently reported systemic adverse clinical reactions that were reported as possibly, probably, or definitely related to PRIMAXIN I.V. (Imipenem and Cilastatin for Injection) were fever, hypotension, seizures (see PRECAUTIONS), dizziness, pruritus, urticaria, and somnolence.

How often do you use imipenem and cilastatina?

Si usa la inyección de imipenem y cilastatina en casa, utilícela aproximadamente a la misma hora todos los días. Siga atentamente las instrucciones que se encuentran en la etiqueta de su receta médica y pida a su médico u otro proveedor de cuidado de salud que le explique cualquier parte que no comprenda.